Reconstructing the Brain in a Dish: Emergence of Neuroinflammation from Retrotransposons

9/12/2017; 7 minutos

Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms.
By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation.
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Stem Cell: Advanced Concepts