Xenoestrogens in Relation to Mammographic Breast Density - a Marker of Breast Cancer Risk - in Postmenopausal Women

9/18/2013; 17 minutes

Bisphenol-A (BPA) is widely accepted as an endocrine disruptor, but evidence is lacking to establish BPA as a breast carcinogen. Human studies of the health effects of BPA are scarce, and studies of BPA are largely limited to laboratory studies. BPA is present in plastic consumer products including canned food linings and #7 polycarbonate plastics. According to recent NHANES data, human exposure is widespread. Amy Trentham-Dietz, University of Wisconsin, describes the results of her study to evaluate the association between BPA exposure and breast cancer risk in adult women. Relations between the three phenols and breast density are presented as well as relations between several sex hormones including estradiol with breast density. Results provide preliminary evidence to guide additional studies on the effects of xenoestrogens like BPA on the risk of breast cancer. (#25029)

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