In the United States, there are over 60,000 new diagnoses and nearly 14,000 deaths from kidney cancer each year. Dr. Won Kim reviews the epidemiology of kidney cancer (including established risk factors), the biology and pathophysiology of kidney cancer, treatment options for localized disease, and the role of systemic therapy in the treatment of advanced, metastatic disease. He also discusses the current and future role of immunotherapy in kidney cancer. Recorded on 07/15/2014. (#28502)