A gene drive is a targeted contagion intended to spread within species, forever altering the offspring. Gene drive enthusiasts say they could wipe out malaria, saving more than half a million lives each year. As yet, no CRISPR gene drive has been released in the wild — few have even been built. Laurie Zoloth of the University of Chicago explores the ethical questions about genes designed to spread through populations and alter ecosystems, and their unforeseen consequences. Recorded on 11/15/2018. (#34183)