As the second anniversary of the start of the COVID-19 pandemic approaches, along with the specter of outbreaks during the winter season, the world continues to grapple with uncertainties of the pandemic. Join UC San Diego experts who describe how epidemic modeling and data-driven approaches led to the strategies behind UC San Diego's Return to Learn program. Scientists also discuss the latest research on proteins known as interferons and their promise as anti-viral COVID-19 therapeutics. And finally, hear from evolutionary biologists about what we've learned about disease transmission, changes from the initial Wuhan virus strain and what these variants could mean for the future of this pandemic. Recorded on 12/02/2021. (#37692)