Edward Chang of UC San Francisco is interested in determining the basic mechanisms that underlie our ability to perceive and produce speech. While much of this processing has been localized to the peri-sylvian cortex, including Broca's and Wernicke's areas, the fundamental organizational principles of the neural circuits within these areas are completely unknown. To address this, his laboratory applies a variety of experimental approaches to examine both local circuitry and global network dynamics spanning multiple cortical and sub-cortical regions with unparalleled spatial and temporal resolution in humans. Recorded on 02/20/2015. (#29405)