The world has lived through 2+ years of the COVID-19 pandemic, heightening the awareness of the links between health and other aspects of life including education and the economy. Future pandemics are a real risk but there are a number of other threats to human health and well-being as well. These include climate change, the rise of obesity, inverted population pyramids, inter-state conflict, rising inequalities, antimicrobial resistance. Counterbalancing these threats are the opportunities that may come through the health sector and broader innovation. Using a comprehensive future health scenario framework, Christopher Murray, professor and chair of Health Metrics Sciences, University of Washington and director of the Institute for Health Metrics and Evaluation, explores the range of future trajectories that may unfold in the 21st century. Recorded on 10/06/2022. (#38271)