ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS

11/8/2018; 6 minutes

Sandrine Da Cruz, PhD and Jone López-Erauskin, PhD explain how ALS causing mutations in FUS inhibit intra-axonal protein synthesis and drive disease without nuclear loss of FUS function. This research appears in the journal Neuron. (#34203)

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