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Razelle Kurzrock, the director of the Center for Personalized Cancer Therapy at the Moores Cancer Center at UC San Diego, presents breakthroughs in genomics and targeted therapies that are being used in clinics and have the potential to revolutionize the practice of oncology. However, to realize that potential, Dr. Kurzrock argues that the old paradigms for treating patients and designing clinical trials must be replaced with approaches that target the abnormal genes in individual tumors and use advanced technological tools to match each patient with the best drug for his or her specific cancer. Dr. Kurzrock was presented by the Center for Ethics in Science and Technology in San Diego.

From Roosevelt to Clinton, many American presidents tried to pass universal coverage but failed. Nevertheless, Obama and the Democratic leadership chose to tackle the issue again and succeeded in getting the Affordable Care (ACA) law passed. Stuart Altman, Former Assistant Secretary of the US department of Health, Education and Welfare explores health reform - what made it necessary, the competing proposals that existed before the ACA was passed, and if it will slow healthcare spending. Recorded on 02/06/2014.

Early detection of Alzheimer's disease - before symptoms are visible - may be a key to stopping the disease's progression. What warning signs are researchers looking for and what tools can they use? Paul Aisen, MD joins William Mobley, MD, PhD to discuss optimal assessments for diagnosing the disease, novel tools making earlier diagnosis possible, and the road map to developing drugs to slow, halt, and prevent Alzheimer's. Recorded on 7/29/2014.

Can lost memories be found? Is it possible to erase a memory from the brain? Roberto Malinow, MD, PhD joins William Mobley MD,PhD to discuss his recent study where memories were not only erased but restored in rats. Learn about how synapses in the brain function and how findings of this study could lead to breakthroughs in the treatment of Alzheimer's disease.

Dr. Sanford Newmark specializes in the integrative and holistic treatment of children with autism and ADHD. He combines conventional medicine with nutrition, behavior management, and various complementary modalities. Dr. Newmark is the head of the Pediatric Integrative Neurodevelopmental Program at UCSF. Recorded on 05/08/2014.

More than 2 million people die every year in the United States, almost always in the presence of life-sustaining medical technology. Sometimes the choices posed by medical technology make death the least worst alternative. Yet, choosing death, or letting go, is often a painful and contentious business. Bioethicist Dr. Stuart Youngner, Case Western Reserve University School of Medicine, explores some of the ways our society and others are coping with this unavoidable dilemma.

Testicular cancer is most common cancer in young men and is a model of a curable cancer. UCSF genitourinary cancer specialist Dr. Terence Friedlander reviews the basic biology of testicular cancer and discusses the management of the disease, focusing on the clinical presentation, management of early stage disease, role of multimodality treatment, survivorship and the long term effects of chemotherapy and radiation, and discuss questions facing the field today, including the role of autologous bone marrow transplantation for advanced disease. Recorded on 07/01/2014.

Barbara Abrams DrPH, RD. Professor of Epidemiology, Maternal and Child Health, and Public Health Nutrition; Head, Epidemiology/Biostatistics Program, UC Berkeley. Recorded on 05/20/2014.

Barbara Laraia PhD, MPH, RD. Associate Professor, Community Health and Human Development; Director, Public Health Nutrition - UC Berkeley. Recorded on 05/20/2014.

Wilbert Mason, MD, MPH, reviews the clinical presentation, diagnostic criteria, and presents the epidemiology of Kawasaki Disease in the U.S. and across the globe.
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