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UCSF Kidney Transplant Program - Update in Transplantation 2013 Part Four: Recurrent FSGS: What's New? Flavio Vincenti, MD discusses the Pursuit of Biomarkers and Treatments for Focal Segmental Glomerulosclerosis (FSGS)

UCSF Kidney Transplant Program - Update in Transplantation 2013 Part Five: The Logistics of Belatacept Therapy. David Wojciechowski, D.O. discusses the use of belatacept for prevention of kidney rejection, as well as patient selection criteria and the protocols for use at UCSF.

Razelle Kurzrock, the director of the Center for Personalized Cancer Therapy at the Moores Cancer Center at UC San Diego, presents breakthroughs in genomics and targeted therapies that are being used in clinics and have the potential to revolutionize the practice of oncology. However, to realize that potential, Dr. Kurzrock argues that the old paradigms for treating patients and designing clinical trials must be replaced with approaches that target the abnormal genes in individual tumors and use advanced technological tools to match each patient with the best drug for his or her specific cancer. Dr. Kurzrock was presented by the Center for Ethics in Science and Technology in San Diego.

Review methods used to study functional interactions and networks with rs-fcMRI and how these methods have been used to define developmental changes in network functional connectivity. The implementation of multivariate pattern analysis methods using support vector machine classification and regression has allowed us to make predictions about the maturity of the brains functional network architecture in individuals. The implications of these approaches for understanding typical and atypical development of the brain's functional network architecture will be discussed.

The way we treat medical conditions is constantly evolving. From new ways of distributing medical information to new drugs and therapies. Alexander Kuo, MD joins David Granet, M.D., F.A.C.S., F.A.A.P. to discuss how he uses shared medical appointments to give his patients in-depth care. Dr. Kuo also highlights new treatments for Hepatitis C.

The panelists discuss their global clinical investigation programs, highlighting creative research approaches and lessons learned. Topics include innovative methods for studying treatment of tuberculosis, infectious and inflammatory eye diseases, and mental health disorders in resource-constrained environments around the world. Each speaker provides case examples, discusses achievements, and shares his or her perspectives on opportunities for furthering UCSF global clinical research initiatives. Panelists: Nisha Acharya, Associate Professor, Departments of Ophthalmology and Epidemiology; Susan Meffert, Assistant Professor, Department of Psychiatry; Payam Nahid, Associate Professor, Department of Medicine. Saam Morshed, Assistant Professor, Department of Orthopaedic Surgery moderates.

Overuse injuries are extremely common. They happen in sports and at work and they affect almost everyone. They occur after repetitive loading rather than traumatic but can be equally problematic for one's health. Dr. Anthony Luke, UCSF department of Orthopaedic Surgery, explores the science of how stress can overwhelm the body's ability to recover, resulting in injury. Understand how imbalance between training loads and recovery can affect athletes at all levels. By understanding the mysteries of the mechanisms for overuse injuries, you can learn how these injuries can be preventable. Recorded on 02/11/2014.

Lord Nigel Crisp, Member, House of Lords UK, is an independent crossbench member of the House of Lords and works mainly on international development and global health. From 2000 to 2006, he was both chief executive of the NHS, the largest health organization in the world, and permanent secretary of the UK Department of Health and led major reforms in the English health system. Recorded on 02/19/2014.
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