The Brain Channel
Alzheimer's Disease
The oncoming epidemic of Alzheimer's disease is staggering to consider. It will have an enormous impact on our personal lives, our communities, and our nation. Join us to explore treatment options, innovations in research, and so much more.

Date: 2/16/2015
What insights into Alzheimer's disease can cutting edge imaging techniques reveal? James Brewer, MD, PhD joins William Mobley, MD, PhD to discuss how this unique wiindow into the brain can be used to study the progression of the disease as well as help test new therapies.

Date: 2/5/2015
How can we create more effective drugs for Alzheimer's disease? Michael Jackson, PhD joins William Mobley, MD, PhD to discuss the process of turning an idea into a drug. Creating connectivity between basic scientists, pharmaceutical companies, and the physicians on the front lines is a critical step as is embracing new ideas that may lead us to new therapeutic options.

Date: 2/2/2015
The biomarkers for many diseases can be found through blood tests, can Alzheimer's disease eventually be diagnosed this way? Douglas R. Galasko, MD joins William Mobley, MD, PhD to discuss the search for these biomarkers and how they might one day lead to earlier and more accurate diagnoses of the disease, improved therapies, clear maps of progression, and much more.

Date: 12/1/2014
Caring for a loved one with dementia can be overwhelming. Dealing with the day to day realities while managing your own mental and physical well being is a constant challenge. Darlene Shiley cared for her late husband as he dealt with dementia. She shares her story with Dr. William Mobley and stresses the importance of palliative care.

Date: 11/7/2014
Six in ten people with dementia will wander. Hear about the programs that are available to help bring them home safe. Linda Cho, executive director of Stellar care, joins William Mobley, MD, PhD to discuss the problem of wandering and how to create a home environment that facilitates safety and comfort.

Date: 11/7/2014
Choosing residential care for a loved one if often a difficult decision. Linda Cho, executive director of Stellar care, joins William Mobley, MD, PhD to talk about the new models of residential care, family involvement, care with dignity and more.

Date: 11/6/2014
Can stem cells be a weapon in the fight against Alzheimer's disease? Larry Goldstein, PhD director the the UC San Diego Stem Cell Program, joins William Mobley, MD, PhD to discuss how stem cells work and what possibilities they may unlock.

Date: 10/22/2014
There are more than 5 million Americans living with Alzheimer's disease. The impacts are felt not only by the patients but by their family, their caregivers, and the community at large. San Diego County Supervisor Dianne Jacob joins William Mobley, MD, PhD to discuss how we can better manage this disease from a public policy standpoint.

Date: 10/16/2014
How do you know when memory problems become more than just problems? Diagnosing Alzheimer's disease can be challenging but new tests and scientific insight are making the process simpler and more accurate. Michael Rafii, MD, PhD joins William Mobley, MD, PhD to discuss when to see a doctor, what to expect during the diagnosis process, and other valuable information for patients and their families.

Date: 10/3/2014
How can communities better support the growing number of people affected by Alzheimer's disease? Mary Ball, president and CEO of the Alzheimer's Association, San Diego and Imperial Counties Chapter joins William Mobley, MD, PhD to discuss how her organization is trying to make a difference through information, support, and partnerships with local government.

Date: 10/2/2014
How do we create and store memories? Larry Squire PhD joins William Mobley MD, PhD to dissect these processes and how we might use this knowledge to aid in the fight against Alzheimer's disease.

Date: 10/1/2014
By the age of 40, nearly all people with Down syndrome have the plaques and tangles associated with Alzheimer's disease. Michael Rafii, MD, PhD joins William Mobley, MD, PhD to discuss why this occurs, the prevalence and progression of Alzheimer's disease, potential treatment models and current research affecting this predisposed population.

Date: 9/15/2014
Can lost memories be found? Is it possible to erase a memory from the brain? Roberto Malinow, MD, PhD joins William Mobley MD,PhD to discuss his recent study where memories were not only erased but restored in rats. Learn about how synapses in the brain function and how findings of this study could lead to breakthroughs in the treatment of Alzheimer's disease.

Date: 9/15/2014
Early detection of Alzheimer's disease - before symptoms are visible - may be a key to stopping the disease's progression. What warning signs are researchers looking for and what tools can they use? Paul Aisen, MD joins William Mobley, MD, PhD to discuss optimal assessments for diagnosing the disease, novel tools making earlier diagnosis possible, and the road map to developing drugs to slow, halt, and prevent Alzheimer's. Recorded on 7/29/2014.

Date: 9/8/2014
What does the future hold for the treatment of Alzheimer's disease? Steven L. Wagner, PhD joins William Mobley, MD, PhD to discuss the development of new drugs to aid in the fight. Wagner describes amyloid plaques as "the cholesterol of the brain" and is working to find a way to suppress its adverse effects.

Date: 12/8/2011
Alzheimer's is a devastating and heartbreaking disease that about 5.4 million Americans are living with today, and experts predict that number will skyrocket to as many as 16 million by 2050. Dr. William Mobley, Distinguished Professor and Chair of the Department of Neurosciences at UCSD, gives an overview of Alzheimer's disease: what it is, why it is seen as an oncoming epidemic, importance of proper diagnosis, pathogenesis of the disease, and new treatments envisioned.